History of Rheumatoid Arthritis

The introduction of TNF- blocking agents is one of the milestones in the therapy of rheumatoid arthritis, parallel to the introduction of cortico-steroids. Edited by Larry Moreland and Paul Emery, experts in rheumatological disease, the book charts the history and development of the concept of tumor-necrosis-factor-alpha (TNF- ) inhibition. The authors document TNF- from its discovery to its now well-documented clinical applications in the treatment of patients with rheumatoid arthritis. They compare and contrast practical management issues concerning the use of these agents both in the US and UK/Europe. The book is a practical and accessible source for the most recent information in this field.

Rheumatoid arthritis - Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. It is a disabling and painful inflammatory condition, which can lead to substantial loss of mobility due to pain and joint destruction.

Juvenile arthritis - Juvenile arthritis is a type of arthritis typically affects children before the age of sixteen. Most children with juvenile arthritis have a form of rheumatoid arthritis, the symptoms of which are identical to the adult kind.

Rheumatoid factor - Rheumatoid factor (RF) is a blood test performed in patients with suspected rheumatoid arthritis (RA). It is an antibody against IgG, which is itself an antibody; RF and IgG form immune complexes, which are part of the disease process of various rheumatological diseases.

Polyarthritis - Polyarthritis is any type of arthritis which involves more than one joint. Polyarthritis is most often caused by an auto-immune disorder such as Rheumatoid arthritis, Psoriatic arthritis, and Lupus erythematosus but can also be cased by infections.

historyofrheumatoidarthritis

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